Antitumor Steroids by R T Blickenstaff PDF

By R T Blickenstaff

Antitumor Steroids examines using steroids, in addition to nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the remedy of melanoma. It explains the mechanism through which steroids and their receptors interact to impact their physiological features in most cases and their antitumor job particularly. It additionally describes the systematic screening of antitumor compounds remoted from normal resources.
Organized into 9 chapters, this ebook starts with an summary of the function of steroids in melanoma therapy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the subsequent chapters reflect on androgens, a few antiandrogens, derivatives in response to C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl workforce. The booklet explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor houses of obviously taking place corticosteroids; sterols and cucurbitacins; diet D and its metabolites; and cardenolides, bufadienolides, and withanolides. The publication concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This ebook is a invaluable source for natural and medicinal chemists biochemists, and pharmacologists attracted to using steroids in treating cancer.

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Antitumor Steroids by R T Blickenstaff

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